Alanine is a nonessential amino acid synthesized in the body through the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine.
D-Alanine, the right-handed form, is the non-proteinogenic variant of alanine, also referred to as D-ala or (R)-alanine. It belongs to the class of organic compounds known as alanine and derivatives and is characterized by its strong basic properties (based on its pKa). D-Alanine is present in all living organisms, spanning from bacteria to humans.
CAS No.: 338-69-2
Molecular Formula: C3H7NO2
Melting Point(°C): 278-282°C
Water Solubility: 155 g/L (20°C)
Appearance: White crystals or crystalline powder
Assay: 98.0% min. (HPLC)
Transmittance: 95.0% min.
Specific rotation[α]D25: -14.3°～-15.3°
Loss on drying: 0.2% max.
Chloride [Cl-]: 0.1% max.
Residue on ignition: 0.2% max.
Heavy metals [Pb]: 10ppm max.
Arsenic [As2O3]: 2ppm max.
D-Alanine plays a crucial role in bacterial cell wall biosynthesis.
It is employed in the study of the specificity and kinetics of alanine racemase(s) (alaR).
D-Alanine is an essential component in the biosynthesis of peptidoglycan crosslinking subunits, which are vital for the construction of bacterial cell walls.